Euphoric Necratosis

Euphoric Necratosis, known as Rapture Rot by the common folk, is a rare and deadly affliction. Its victims experience constant escalations in their emotions, ranging from intense joy to uncontrollable anger or sadness; each "emotional episode" destabilises the physical form of the patient. The disease targets random limbs from the victims' bodies, causing the limbs to start liquifying. Some cases saw the heads of victims start liquifying first, leading to instant death.
Each emotional tumult caused by Rapture Rot only accelerates this woeful process.

There is no known cure for it, as a victim's body and mind succumbs to its vile tendrils and gets pulled into utter chaos; the only way out is by ending one's miserable existence. The disease is rare, that is true, but whenever it ensnares a poor sap, a "Wry Goodbye" is done, a ritual of sorts to help the person pass into the other world peacefully; they get administered a lethal dose of rat poison (or something more expensive if they've got the money for that). And are surrounded by their loved ones or any of the cheap whores that they promised payment after they pass. The victim can enjoy their heightened emotions until having their last laugh, if you will.

The disease is contracted by random deep bites on a victim's back. No one knows where they come from, but everyone knows you're as good as dead once you get them. However, many wives' tales and rumours speak of the Gloomfang Noctilisk, long and slender creatures that stalk the woods. Still, no civilised person would believe tales spun to scare kids, would they...?

This gruesome progression of Euphoric Necratosis can be tracked by a D-10 table I graciously provided below in case you want to add this into one of your sessions (look at you being an evil GM). The rate of the disease's acceleration is up to you, the Gamemaster; make it as rapid or slow, reduce its lethality, whatever; it is yours to mess about with.

The Horrifying and Gruesome Progression of Euphoric Necratosis:

Roll	Effect
1	Right Hand/Arm: Fingers to shoulder, the right arm begins its unsettling transformation, turning to a liquid state.
2	Left Hand/Arm: The left arm suffers a similar fate, with each segment dissolving in an agonizing sequence.
3	Right Foot/Leg: Starting from the toes, the disease mercilessly claims the right leg, rendering it a useless, liquid mass.
4	Left Foot/Leg: The left leg's turn to succumb to the disease, from the toes upward, leaving victims crippled and in despair.
5	Torso: The core of the body is not spared; the torso's liquefaction leads to catastrophic organ failure.
6	Head: A dire roll leading to the most feared outcome - head liquefaction, often resulting in instant or rapid death.
7	Eyes: Vision is stolen as the eyes melt away, plunging victims into darkness before further spread.
8	Ears: The ears begin to dissolve, taking away hearing and potentially leading to total disorientation.
9	Nose and Mouth: The essential functions of breathing and eating are compromised as the face begins its decay.
10	Roll Twice: The disease's ferocity shows no bounds; roll twice more to see multiple areas afflicted at once.